Golden Globe winner Hugh Laurie, wonderfully cast against type, stars as the brilliant but caustic Dr. Gregory House, a maverick physician who is devoid of bedside manner. While his behaviour can border on the antisocial, Dr. House thrives on the challenge of solving medical puzzles that other doctors give up on. Together with his handpicked team of young medical experts, he'll do whatever it takes in the race against the clock to solve the case...