Giratina is the sole Pokémon living in the Reverse World, a little-known realm adjacent to our own. Enraged when Palkia and Dialga disrupt time and space, it drags Dialga into the Reverse World for a battle but the conflict is broken up by a tiny Shaymin, the Gratitude Pokémon! After departing the Reverse World and meeting Ash and his friends, Shaymin communicating telepathically asks for help, and soon after Ash and his friends agree to assist Shaymin, they're dragged into the Reverse World and meet Newton Graceland, who's been researching the mysterious realm. Little do they know that Newtown's former assistant, Zero, seeks to harness Giratina's power to rule the Reverse World, even if that means destroying the real world! Can our heroes and their Pokémon thwart Zero's evil plans and protect both worlds? Will Giratina resolve its differences with Dialga? And what will Ash and his friends learn about that special Shaymin?